Write down key personal information, including prior surgeries or pelvic radiation, any major stresses, or recent life changes. This is not proof that finasteride is to blame, since a variety of medical conditions and other prescription drugs could explain the sexual symptoms. Do a physical exam, which will likely include an exam of your penis, testicles and rectum. The presence of side effects during pharmacological treatment is unfortunately a quite common problem. Im suffering from pfs for 3+ years now so pfs is very real sadly but I believe the dudes article is the best explenation Ive read so far. Its like they want to hide possible solutions. "I had a case of PFS that was a severe as it gets. Now I can happily say that I no longer have any problem, strong erection all day and all night. I had all the classic symptoms. Minoxidil is FDA approved for genetic hair loss - it does not help other conditions quite so much. Minoxidil takes 4-6 months before an individual should assess whether or not it helps. The problem is that most docs prescribe it at excessively high levels (5 mg/day). Ask questions about your symptoms and how long you've had them. Serious Side Effects: Post Finasteride Syndrome Maybe if theyre lucky in 10 years. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). This content does not have an Arabic version. Indian J Plast Surg. Next to no sensitivity in my genitals. Hello, some finasteride users have reported the reversal of post-finasteride syndrome using HCG as therapy. Recovered from Post Finasteride Syndrome! : r/tressless The results have been amazing and far too great to chalk it up to just being a placebo. Your doctor might ask: Mayo Clinic does not endorse companies or products. I remember being depressed, emasculated, and hopeless. -. Finasteride blocks the metabolism of testosterone. 2008;35:211. This stuff WORKS. Management of the dry ejaculate: A systematic review of aspermia and retrograde ejaculation. If a high volume of sperm is found in your urine, you have retrograde ejaculation. Andracim Gel (small 2 eminem size, 1 on each size of rib cage, less is more with this stuff). The guy who made this thread and gave his opinion was banned too. Res. Endocrinol. The article stated proviron was the best potential cure in his opinion. Better to learn the cause of PFS and create a cure based on that. I'm not going to go into the entire history of what post finasteride syndrome is, and I assume many of you looking into buying Tribulus know exactly what it is. Li X, Guo Y, Lu Y, Li H, Yan S, Li H, Li Y. Transl Androl Urol. I will tell you how I solved my problem with post-finasteride syndrome, which produces no erections or little libido even if you have stopped taking the famous drug years ago. Accessed Oct. 28, 2021. Just bombarding their bodies with strong androgens. While we do connect people with vetted, board-certified doctors, we dont provide medical consultations, diagnosis, or advice. I know how I feel and I know it's working. In: Ferri's Clinical Advisor 2022. I was one of the lucky guys who recovered from Test injections, https://old.reddit.com/r/steroids/comments/igyd61/offtopic_daily_chat_20200826/g2ym80n/. I feel deeply for all my balding brothers out there who are suffering from this poison. No content on this site, regardless of date, should ever be used as a substitute for direct medical advice from your doctor or other qualified clinician. -, Alkahtane A.A., Albasher G., Al-Sultan N.K., Alqahtani W.S., Alarifi S., Almeer R.S., Alghamdi J., Ali D., Alahmari A., Alkahtani S. Long-term treatment with finasteride induces apoptosis and pathological changes in female mice. After stopping, I got ED, extreme fatigue, brain fog, no libido and lethargy. Disorders of male orgasm and ejaculation. ._1LHxa-yaHJwrPK8kuyv_Y4{width:100%}._1LHxa-yaHJwrPK8kuyv_Y4:hover ._31L3r0EWsU0weoMZvEJcUA{display:none}._1LHxa-yaHJwrPK8kuyv_Y4 ._31L3r0EWsU0weoMZvEJcUA,._1LHxa-yaHJwrPK8kuyv_Y4:hover ._11Zy7Yp4S1ZArNqhUQ0jZW{display:block}._1LHxa-yaHJwrPK8kuyv_Y4 ._11Zy7Yp4S1ZArNqhUQ0jZW{display:none} After stopping 7 weeks later (when I ran out of my proviron), things felt off for a few weeks but then after around two months I got back to my pre-PFS state. 2022 Oct;11(10):1452-1457. doi: 10.21037/tau-22-92. What the hell? I know it's been a LONG time and also want to tell everyone that I'm cured from PFS great news. His article with all the studies hes referencing: Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. Samplaski MK, et al. I have been prescribed a 2.5% DHT gel that is applied to the shoulders and forehead once a day. 2015;104:107. I also tried testosterone treatment but it had almost no effect regardless of dosage. Elsevier; 2021. https://www.clinicalkey.com. Of course there are some people with severe pfs but even then just wait is shit advice. Best, Dr. Emer. Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: Imipramine, an antidepressant. Of course I said this in a respectable manner Result: post deleted and banned. This report will provide you with the information you need to understand the current controversies, avoid common pitfalls, and work with your doctor to make informed choices about your prostate health. No interest in sex at all. Ive been doing this for over 2 years and have ZERO sexual side effects from the drug. PMC On a sidenote i've seen a few other people recover the same way. I could be wrong but none of them seem to have anhedonia or genital numbness or fatigue or insomnia or anything, just libido and ED issues. Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. Answer: Hormonal optimization while on finesteride there are many options including peptides, and HCG as well as clomid/arimidex. Studies show it can help slow or reverse the process of hair loss. Tamoxifen I did 20mg during the four weeks every day. What's the best treatment to use to try to get my partner pregnant? If your doctor thinks drugs you are taking might be affecting your ability to ejaculate normally, he or she might have you stop taking them for a period of time. My life is finally back. Thanks for visiting. When dosed properly, it can bring DHT within normal ranges very effectively. However, some men report persistent sex drive and ejaculation problems after stopping the medication. This is a summary of the protocol which I followed for 6 months which eventually cured me. Pornography usually has to be in the picture but there are RARE times when I get a spontaneous boner I can play with that will stick around and I can achieve orgasm with or without pornography. Thats probably the worst part if you only read that forum youre pretty much going to feel hopeless. Best, Dr. Emer. Post-Finasteride Syndrome: how to resolve it by Is there a generic alternative to the medicine you're prescribing me? Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Book: Mayo Clinic Guide to Fertility and Conception. Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron, of course he doesnt have any affliate links to those products. I suspect its because my E2 was so low already and that made it feel even lower (single digits if I recall correctly). doi: 10.1177/0960327119842195. The drug has a very short half life in the bode, but the $1,000,000 question is whether there a a long-term alteration in DHT production and/or effectiveness. Mesterolone (Proviron) is one of the best compounds that can be used for treating Post Finasteride Syndrome in my opinion. All rights reserved. https://forum.propeciahelp.com/t/cured-after-11-years/42363. Fertil Steril. Depending on the likely cause of your dry orgasms and whether you need evaluation and treatment to help you get your female partner pregnant, you might need to see a urinary and reproductive specialist (urologist). Fertility and Sterility. Around 8 months and i was pretty much recovered. If youre experiencing a medical issue, please contact a healthcare professional or dial 911 immediately. Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. https://old.reddit.com/r/steroids/comments/m5m7o9/help_steroids_for_pssd/gr0uhqj/. Would you like email updates of new search results? Post Finasteride Syndrome Recovery - YouTube I read about the Post-Fin Syndrome and decided to quit (Almost) No erections, no libido. Epub 2010 Dec 22. Est. I suggest you see an expert for internal workup, we do this frequently in our practice. To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. And youre competely right, they make it sound like youre doomed and you shouldnt try anything but wait for the Baylor study and fill out the surveyDo they really expect some magical cure to come out when Baylor releases or their survey has enough participants? Look, it's as simple as this. Understanding all of your options and communicating with your doctor and partner can help. A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. While most men can get their female partners pregnant with infertility treatment, it can be costly and require stressful medical procedures for both you and your partner. Chicago Man: Taking Propecia is the Biggest Regret Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: These medications help keep the bladder neck muscle closed during ejaculation. https://www.isarms.com/forums/threads/post-finasteride-syndrome.18175/. Neuroactive steroid levels are modified in cerebrospinal fluid and plasma of post-finasteride patients showing persistent sexual side effects and anxious/depressive symptomatology. Mild side effects that have been reported with finasteride include: ejaculation problems. Retrograde ejaculation - Diagnosis and treatment - Mayo Clinic Do you have cloudy urine after an orgasm? Adverse effects of common medications on male fertility. ._2cHgYGbfV9EZMSThqLt2tx{margin-bottom:16px;border-radius:4px}._3Q7WCNdCi77r0_CKPoDSFY{width:75%;height:24px}._2wgLWvNKnhoJX3DUVT_3F-,._3Q7WCNdCi77r0_CKPoDSFY{background:var(--newCommunityTheme-field);background-size:200%;margin-bottom:16px;border-radius:4px}._2wgLWvNKnhoJX3DUVT_3F-{width:100%;height:46px} Incredible! Should I worry about finasteride side effects even after At higher doses, finasteride (Proscar) can also treat benign prostatic hyperplasia (BPH). Key takeaways: Finasteride is an FDA-approved medication that treats hair loss in men. Finasteride is available as a lower-cost generic. Feeling dissociated and never present. /*# sourceMappingURL=https://www.redditstatic.com/desktop2x/chunkCSS/TopicLinksContainer.3b33fc17a17cec1345d4_.css.map*/I had no libido, my erections were weak and i couldnt sustain them. Finasteride Post Finasteride Syndrome For details, see text. Therefore, I cut the pills in half (2.5mg) and toss the other half. 2020 Jan;113(1):21-50. doi: 10.1016/j.fertnstert.2019.11.030. .Rd5g7JmL4Fdk-aZi1-U_V{transition:all .1s linear 0s}._2TMXtA984ePtHXMkOpHNQm{font-size:16px;font-weight:500;line-height:20px;margin-bottom:4px}.CneW1mCG4WJXxJbZl5tzH{border-top:1px solid var(--newRedditTheme-line);margin-top:16px;padding-top:16px}._11ARF4IQO4h3HeKPpPg0xb{transition:all .1s linear 0s;display:none;fill:var(--newCommunityTheme-button);height:16px;width:16px;vertical-align:middle;margin-bottom:2px;margin-left:4px;cursor:pointer}._1I3N-uBrbZH-ywcmCnwv_B:hover ._11ARF4IQO4h3HeKPpPg0xb{display:inline-block}._2IvhQwkgv_7K0Q3R0695Cs{border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._2IvhQwkgv_7K0Q3R0695Cs:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B{transition:all .1s linear 0s;border-radius:4px;border:1px solid var(--newCommunityTheme-line)}._1I3N-uBrbZH-ywcmCnwv_B:focus{outline:none}._1I3N-uBrbZH-ywcmCnwv_B.IeceazVNz_gGZfKXub0ak,._1I3N-uBrbZH-ywcmCnwv_B:hover{border:1px solid var(--newCommunityTheme-button)}._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk._35hmSCjPO8OEezK36eUXpk{margin-top:25px;left:-9px}._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:focus-within,._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP._3aEIeAgUy9VfJyRPljMNJP:hover{transition:all .1s linear 0s;border:none;padding:8px 8px 0}._25yWxLGH4C6j26OKFx8kD5{display:inline}._2YsVWIEj0doZMxreeY6iDG{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-metaText);display:-ms-flexbox;display:flex;padding:4px 6px}._1hFCAcL4_gkyWN0KM96zgg{color:var(--newCommunityTheme-button);margin-right:8px;margin-left:auto;color:var(--newCommunityTheme-errorText)}._1hFCAcL4_gkyWN0KM96zgg,._1dF0IdghIrnqkJiUxfswxd{font-size:12px;font-weight:700;line-height:16px;cursor:pointer;-ms-flex-item-align:end;align-self:flex-end;-webkit-user-select:none;-ms-user-select:none;user-select:none}._1dF0IdghIrnqkJiUxfswxd{color:var(--newCommunityTheme-button)}._3VGrhUu842I3acqBMCoSAq{font-weight:700;color:#ff4500;text-transform:uppercase;margin-right:4px}._3VGrhUu842I3acqBMCoSAq,.edyFgPHILhf5OLH2vk-tk{font-size:12px;line-height:16px}.edyFgPHILhf5OLH2vk-tk{font-weight:400;-ms-flex-preferred-size:100%;flex-basis:100%;margin-bottom:4px;color:var(--newCommunityTheme-metaText)}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX{margin-top:6px}._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._19lMIGqzfTPVY3ssqTiZSX._3MAHaXXXXi9Xrmc_oMPTdP{margin-top:4px} Is my condition likely temporary or chronic? This site needs JavaScript to work properly. Perhaps if I had tried it longer it would have helped more, Im not sure. Accessed Sept. 15, 2016. Traish AM, Melcangi RC, Bortolato M, Garcia-Segura LM, Zitzmann M. Rev Endocr Metab Disord. Many men with retrograde ejaculation are able to get their partners pregnant once they seek treatment. Am I at risk of complications from this condition? Feeling low-grade depression constantly. Ive seen many others who give their opinion but are banned as a result. Get helpful tips and guidance for everything from fighting inflammation to finding the best diets for weight lossfrom exercises to build a stronger core to advice on treating cataracts. This is because (in the USA) it is only approved for BPH at 5mg and insurance companies will reject claims when it is prescibed at 1mg, which is the only other available dosage. Adverse effects of 5-reductase inhibitors: What do we know, don't know, and need to know? An official website of the United States government. In this review, we focused our attention on adverse events related to 5 alpha-reductase (5-R) inhibitors (i.e., finasteride and dutasteride), approved for the treatment of benign prostatic hyperplasia and androgenetic alopecia (AGA). -, Basaria S., Jasuja R., Huang G., Wharton W., Pan H., Pencina K., Li Z., Travison T.G., Bhawan J., Gonthier R., Labrie F., Dury A.Y., Serra C., Papazian A., O'Leary M., Amr S., Storer T.W., Stern E., Bhasin S. Characteristics of men who report persistent sexual symptoms after finasteride use for hair loss. To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. Unauthorized use of these marks is strictly prohibited. The site is secure. Reuters I guess that never happened. My hair loss is back full force, but so is my libido and so are my erections. Post and transmitted securely. Yeah, that guy's comment history is really puzzling: When i dared visit PFS forums, the most miserable users there were still in a better state than me. WebDr Jordan Grant and Gil T talk about Post Finasteride Syndrome Recovery (PFS recovery). Metabolism of progesterone and testosterone into 5alpha-reduced metabolites and their mechanisms of action: effects of finasteride and dutasteride. Pumpkin Seed Oil-Loaded Niosomes for Topical Application: 5-Reductase Inhibitory, Anti-Inflammatory, and In Vivo Anti-Hair Loss Effects. National Library of Medicine https://www.amazon.com/reviews/R3OGTPUQ1CP005. Yeah the joe_kool guy or whatever his name is had really good luck with TRT, he is honestly the reason I went down this road. I cannot say enough about this. Other: Issues retaining and producing muscle, rectal muscle pain, spike in lower-abdomen fat, also has anyone noticed a rapid increase in earwax production? After numerous labs, I have determined that a dose of 2-3 mg is optimal for keeping my DHT within the normal range. .FIYolDqalszTnjjNfThfT{max-width:256px;white-space:normal;text-align:center} Im talking about the physical inability to have erections and sex drive". Careers. Side effects of treatment with 5 alpha-reductase inhibitors in experimental models. A. Finasteride (sold as Proscar and generic brands) is prescribed for symptoms of an enlarged prostate; it's also used at a lower strength (under the name Propecia) for male pattern baldness. To date, the PFS Foundation has identified 104 such professionals who have published scientific findings and/or voiced opinions on causative links between finasteride and PFS. Some of these same doctors and researchers are also members of our Medical Professionals team, counseling PFS patients and their loved ones worldwide. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. The common denominator in how I feel is Tribulus, period, end of sentence. Fertility and Sterility. As a service to our readers, Harvard Health Publishing provides access to our library of archived content. Common finasteride side effects include loss of libido, breast enlargement, erectile dysfunction (ED), and lower ejaculatory volume. Very controversial topic in this forum. Ketamine for treatment-resistant depression: When and where is it safe? 2016;101:46694680. Nature Reviews Urology. You can't get worse than living with no dick dude. The .gov means its official. As a 5-alpha reductase inhibitor, finasteride works by inhibiting the effects of the enzyme thats responsible for converting testosterone into dihydrotestosterone (DHT). I took a prescription-strength anti-estrogen, Tamoxifen 10mg, twice a day: one at around 3pm and another one together with my test booster before bedtime. These hippocampal neurogenesis changes after finasteride treatment have been linked to emotional behavior and this might contribute to the pathophysiology of affective disorders in humans. I cycled herbal androgen boosting supplements combined with intense workouts (I am a bodybuilder). .c_dVyWK3BXRxSN3ULLJ_t{border-radius:4px 4px 0 0;height:34px;left:0;position:absolute;right:0;top:0}._1OQL3FCA9BfgI57ghHHgV3{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex;-ms-flex-pack:start;justify-content:flex-start;margin-top:32px}._1OQL3FCA9BfgI57ghHHgV3 ._33jgwegeMTJ-FJaaHMeOjV{border-radius:9001px;height:32px;width:32px}._1OQL3FCA9BfgI57ghHHgV3 ._1wQQNkVR4qNpQCzA19X4B6{height:16px;margin-left:8px;width:200px}._39IvqNe6cqNVXcMFxFWFxx{display:-ms-flexbox;display:flex;margin:12px 0}._39IvqNe6cqNVXcMFxFWFxx ._29TSdL_ZMpyzfQ_bfdcBSc{-ms-flex:1;flex:1}._39IvqNe6cqNVXcMFxFWFxx .JEV9fXVlt_7DgH-zLepBH{height:18px;width:50px}._39IvqNe6cqNVXcMFxFWFxx ._3YCOmnWpGeRBW_Psd5WMPR{height:12px;margin-top:4px;width:60px}._2iO5zt81CSiYhWRF9WylyN{height:18px;margin-bottom:4px}._2iO5zt81CSiYhWRF9WylyN._2E9u5XvlGwlpnzki78vasG{width:230px}._2iO5zt81CSiYhWRF9WylyN.fDElwzn43eJToKzSCkejE{width:100%}._2iO5zt81CSiYhWRF9WylyN._2kNB7LAYYqYdyS85f8pqfi{width:250px}._2iO5zt81CSiYhWRF9WylyN._1XmngqAPKZO_1lDBwcQrR7{width:120px}._3XbVvl-zJDbcDeEdSgxV4_{border-radius:4px;height:32px;margin-top:16px;width:100%}._2hgXdc8jVQaXYAXvnqEyED{animation:_3XkHjK4wMgxtjzC1TvoXrb 1.5s ease infinite;background:linear-gradient(90deg,var(--newCommunityTheme-field),var(--newCommunityTheme-inactive),var(--newCommunityTheme-field));background-size:200%}._1KWSZXqSM_BLhBzkPyJFGR{background-color:var(--newCommunityTheme-widgetColors-sidebarWidgetBackgroundColor);border-radius:4px;padding:12px;position:relative;width:auto} Plus, get a FREE copy of the Best Diets for Cognitive Fitness. Accessed Oct. 28, 2021. @keyframes _1tIZttmhLdrIGrB-6VvZcT{0%{opacity:0}to{opacity:1}}._3uK2I0hi3JFTKnMUFHD2Pd,.HQ2VJViRjokXpRbJzPvvc{--infoTextTooltip-overflow-left:0px;font-size:12px;font-weight:500;line-height:16px;padding:3px 9px;position:absolute;border-radius:4px;margin-top:-6px;background:#000;color:#fff;animation:_1tIZttmhLdrIGrB-6VvZcT .5s step-end;z-index:100;white-space:pre-wrap}._3uK2I0hi3JFTKnMUFHD2Pd:after,.HQ2VJViRjokXpRbJzPvvc:after{content:"";position:absolute;top:100%;left:calc(50% - 4px - var(--infoTextTooltip-overflow-left));width:0;height:0;border-top:3px solid #000;border-left:4px solid transparent;border-right:4px solid transparent}._3uK2I0hi3JFTKnMUFHD2Pd{margin-top:6px}._3uK2I0hi3JFTKnMUFHD2Pd:after{border-bottom:3px solid #000;border-top:none;bottom:100%;top:auto} At some point you just cant store it all or want to use old drug. .s5ap8yh1b4ZfwxvHizW3f{color:var(--newCommunityTheme-metaText);padding-top:5px}.s5ap8yh1b4ZfwxvHizW3f._19JhaP1slDQqu2XgT3vVS0{color:#ea0027} (Read up on desensitization of Leydig Cells but don't get nervous at this plan) The symptoms of PFS start to subside within four to eight months after discontinuing the medicine. After 4 months of no progress whatsoever I tried the regimen that saved me - at least thats the only explanation I have. After taking 50mg of Proviron I got my first erection in years. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal After I got PFS my libido died, I stopped liking women, my brain wouldn't work, and my personality changed to a 90 old man. WebA deterioration in the quality of life in affected individuals does not justify use of the drug. I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. A community dedicated to people suffering long term effects after taking 5-ar inhibitors such as Propecia/Finasteride, or for people who wish to know more about the constellation of symptoms commonly known as Post Finasteride Syndrome. And yeah I know hackstasis, looks to be a much better community and forum than propeciahelp without fascist mods. Amedical opinion on this procedure would be important, because we do not have scientific evidence about HCG and PFS, but it would already be a start. If we cant discuss potential cures then that forum is completely worthless and I start to doubt their real intentions.
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